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Introduction The World health organization WHO defines acute
2019-04-22

Introduction The 2008 World health organization (WHO) defines acute leukemias with ambiguous lineage (ALAL) as those leukemias which show no clear differentiation towards either myeloid or lymphoid lineage. It includes acute undifferentiated leukemias which express no specific markers for both line
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br AML therapies with curative intent br Alternative
2019-04-22

AML therapies with curative intent Alternative treatment strategies Targeted therapies: the new kids on the block The recognition of specific mutations as genetic drivers or facilitators of AML has led to the development of new inhibitors and targeted treatment options. New promising drug c
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Interpretation Stakeholders from sectors not historically en
2019-04-22

Interpretation Stakeholders from sectors not historically engaged in health care are forming unique partnerships with common goals and a willingness to address the challenge of global cancer care. Funding None. Declaration of interests Abstract Background Since 2013 medical students from North
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Good news from the Americas illuminated the global
2019-04-22

Good news from the Americas illuminated the global health scene in September. As the Ministers of Health from the western hemisphere gathered in Washington, DC, USA, for PAHO\'s 55th Directing Council, a series of announcements confirmed the New World\'s role as a pioneer of sorts in disease prevent
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Holter ECG monitoring was performed after the patient consum
2019-04-22

Holter ECG monitoring was performed after the patient consumed 180mL of sake (alcohol) each night in both the DDD-R and DDD-CLS modes. The mean HR in the DDD-CLS mode (68bpm) was similar to that (71bpm) in the DDD-R mode, but during sleep, the atrial pacing ratio (43.2%) in DDD-CLS was significantly
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Common and rare SCN A variants
2019-04-22

Common and rare SCN10A variants may contribute to AF susceptibility [59,60]. SCN10A mutations (R14L and R1268Q) cause a loss of function of Nav1.5 current, which is expected to reduce excitability and lead to the development of the arrhythmogenic substrate responsible for BrS and AF. A common varian
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More than million almost children younger than
2019-04-22

More than 200 million—almost 40%—children younger than 5 years in developing countries are not fulfilling their developmental potential. In parts of Africa, up to three-quarters of children are victims of physical abuse, and a third of girls and more than 10% of boys are victims of sexual abuse. One
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br A modo de conclusi n La re
2019-04-22

A modo de conclusión La re/visión que se ha propuesto en el presente escrito recoge el sentido que le da Adrienne Rich al término: revisar es volver a mirar desde un posicionamiento crítico en un presente, desde el que se tiene una perspectiva (temporal) de cómo ha sido la suerte del fenómeno que
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br Material and methods br Results br
2019-04-22

Material and methods Results Discussion Activated microglia has been shown to be a hallmark of central nervous system (CNS) inflammation, which further mediating the subsequent neuronal apoptosis [1], [2], [3], [27], [28]. However, the underlying molecular mechanisms have not been well eluc
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These results have to be interpreted with respect
2019-04-20

These results have to be interpreted with respect to present trends in age at childbearing. Worldwide, adolescent fertility rates fell from 71 to 52 per thousand women aged 15–19 years between the 1970s and the 2000s. This Sulindac sulfide was seen in all regions, with the possible exception of Lat
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En las relaciones pol ticas tradicionales
2019-04-20

En las relaciones políticas tradicionales mapuche, el longko o autoridad tuvo la función de repartir las tierras, prerrogativa que perdió con los desplazamientos y las reducciones, situación que en unión al hecho de que los distintos gobiernos regidos por la intención del trato igualitario para los
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tropisetron Predicting the potential effects of climate chan
2019-04-20

Predicting the potential effects of climate change on the incidence and distribution of infectious gastroenteritis can assist public health providers to control and prevent severe outbreaks in the future. Implementation of programmes for rotavirus vaccination clearly shows benefit and should be an t
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br Los dos libros que a
2019-04-20

Los dos libros que pdgfr inhibitor continuación se reseñan solo en parte coinciden en su objeto de estudio y el método de tratarlo. El libro de Hugo J. Verani ofrece una minuciosa interpretación de la poética de Octavio Paz, especialmente de la que domina en sus poemas extensos. También Evodio Esc
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El poeta becario no es la nica figura que impacta
2019-04-20

El poeta becario no es la única figura que impacta Asiaticoside esta generación; hay otra menos visible, pero que sin duda resulta también relevante para un campo como la poesía, de escaso interés comercial. En los espacios alternativos que no participan de la normativa burocrática, se crean figuras
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br In this issue of
2019-04-20

In this issue of , Tiffany Chao and colleagues present a systematic, comprehensive, and critical assessment of published estimates of the cost-effectiveness of essential surgery, and thus make an important contribution to the published work on the economics of global health interventions. Their he
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