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The study looking at the recovery of
2020-08-03

The study looking at the recovery of cellular material showed that there was a higher percentage of recovery of DNA as a result of swabbing a non-stained fingermark than when applying DD to the fingermark and then collecting with a swab. DD, which is an external binder, binds to the sugar phosphate
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Saururus chinensis Lour Baill Saururaceae a perennial herb i
2020-08-03

Saururus chinensis (Lour.) Baill. (Saururaceae), a perennial herb, is widely cultivated in China and southern Korea. It has been traditionally used as folk medicine for the treatment of inflammation, jaundice and Berberine [8]. Previous chemical studies of S. chinensis have revealed the presence of
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The importance of EBI for B
2020-07-31

The importance of EBI2 for B cell function was first suggested by the dramatic upregulation of this receptor in EBV-transformed Bax inhibitor peptide P5 and further inferred from its regulation in activated and GC B cells (Birkenbach et al., 1993, Glynne et al., 2000, Shaffer et al., 2000). An invo
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The following are the supplementary data related to this art
2020-07-31

The following are the supplementary data related to this article. Acknowledgements This work was supported by grants from the National Natural Science Foundation of China (Nos. 91029716, 81072667, and 81125023) and the National Science and Technology Major Projects for “Major New Drugs Innovatio
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The use of manganese as divalent
2020-07-31

The use of manganese as divalent cofactor instead of magnesium increased TLS across abasic sites (Figure 3C) as well as de novo DNA synthesis (Figures 4C and 5; Figure S5). Although the roles of divalent metal ions in DNA synthesis have been controversial, a number of recent findings suggest a physi
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We have shown that the glycation of collagen
2020-07-30

We have shown that the glycation of collagen hinders collagen-DDR2 binding. McCarthy et al. previously showed reduced binding of rat osteosarcoma-derived cells (UMR106) to glycated collagen. The authors speculated that glycation of collagen attenuates collagen binding to collagen-specific integrins
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Cellular interactions with collagens are
2020-07-30

Cellular interactions with collagens are mediated, to a large part, by cell-surface receptors of the integrin family, which recognise discrete amino ache inhibitor sequences in triple-helical collagen. An important integrin-binding sequence is GFOGER,22, 23 which is present in a number of different
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During maize germination DNA replication
2020-07-30

During maize germination DNA replication starts by 12 h after imbibition [23]. PCNA protein levels increase since the start of imbibition and stabilize by the time replication starts [24]. During this process, the homotrimer of PCNA would seem to form part of protein complexes of molecular mass fluc
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AON successfully alleviated the myotonic phenotype
2020-07-30

AON successfully alleviated the myotonic phenotype in DM model mice [18], [23]. To screen for an optimal AON sequence, we used 25-mer phosphorothioate 2′ O-methyl RNA molecules that covered the Vancomycin hydrochloride 6B or exon 7A. Unexpectedly, AON 7A (+63−8) which covers the boundary of intron
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Endothelial progenitor cells EPCs play key roles in the
2020-07-29

Endothelial progenitor cells (EPCs) play key roles in the process of endothelial repair and replacement for vascular homeostasis and neoangiogenesis [14]. In type 2 diabetes patients, EPCs are known to be reduced. A recent study reported that linagliptin acutely increases the number of endothelial p
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br Experimental Procedures br Author Contributions br Acknow
2020-07-29

Experimental Procedures Author Contributions Acknowledgments We thank Laurentino Villar for protein purifications, Dr. Miguel de Vega for valuable suggestions and critical reading of the manuscript, and Professor Luis Blanco for helpful discussions and the [γ-32P]ATP-(dGMP)n ladder. M.S.’s
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br Acknowledgments This work was financially supported throu
2020-07-29

Acknowledgments This work was financially supported through grantsfrom National Natural Science Foundation of China (No. 21402105), and Shenzhen Municipal government SZSITIC (JCYJ20160301153753269). Introduction Due to their unique physical, electrical, and optical properties, ultrasmall fluo
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In the present study we
2020-07-29

In the present study, we examined the methylation rates of the TREM2 intron 1 in leukocytes of AD subjects and investigated the relationship between these methylation rates and TREM2 mRNA expression. Materials and methods Result Discussion This is the first study showing TREM2 DNA hypometh
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In terms of the viability neither the BA nor the
2020-07-29

In terms of the viability neither the BA3 nor the BA4 product has been compromised, probably due to the physiology of the microorganism. To successfully formulate CPA-8, the endospore form was used (Gotor-Vila et al., 2017d). The inherent stability of these structures enabled them to remain quiescen
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Since the early s changes in demographics and the global
2020-07-29

Since the early 1990\'s, changes in demographics and the global business environment have caused worry within the accounting profession about the supply chain of entry level accountants, both in terms of quantity and quality (Black, 2012). More recent predictions are that 75 percent of Certified Pub
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