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To date no biomarker analyses of response
2019-05-31
To date, no biomarker analyses of response to VEGFR targeting agents in breast cancer patients with bone predominant metastatic disease has occurred. Although the bone turnover markers serum c-telopeptide (sCTx), and urinary N-telopeptide (uNTx) were measured at baseline, and uNTX measured every 8 w
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Introduction Cardiac resynchronization therapy CRT reduces m
2019-05-31
Introduction Cardiac resynchronization therapy (CRT) reduces mortality and morbidity in selected heart failure patients with impaired left ventricular (LV) function and cardiac dyssynchrony [1]. Most patients receive CRT with a defibrillator (CRT-D) because the indications for an implantable cardio
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order CA-074 Me Juan Tovar dramaturgo y cr tico teatral pres
2019-05-31
Juan Tovar, dramaturgo y crítico teatral p order CA-074 Me esenta en su texto “Los siete géneros”, la teoría que aprendió durante su paso por las aulas de la maestra Luisa Josefina Hernández y cuyas lecciones no obstante su continuo estudio y aplicación por directores y actores en talleres y escuela
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br Las fuerzas Impulsoras de la Internacionalizaci n de la
2019-05-30
Las fuerzas Impulsoras de la Internacionalización de la ciencia y la technología en América latina Los eLementos indicativos de la internacionalizacion de la ciencia y la tecnología en América Latina Debates ytensiones en torno de la internacionalización de la ciencia y la technología en Amé
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The option tested by Berkley and colleagues is the
2019-05-30
The option tested by Berkley and colleagues is the use of prolonged antimicrobial prophylaxis after clinical nutritional recovery. The concept of empirical broad-spectrum antimicrobial therapy in high-risk immunocompromised populations is not novel, as there have been decades now of demonstrated ben
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The presence of an inflammatory infiltrate
2019-05-30
The presence of an inflammatory infiltrate is associated with poor prognosis in a number of malignancies, including those with a predilection for metastasis to bone. CAFs are capable of promoting, and maintaining an inflammatory environment by recruiting immune cells; in particular monocyte/macropha
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Sin embargo no se puede hablar de
2019-05-30
Sin embargo, no se puede hablar de etapas delimitadas con absoluta precisión; la revista Simpleton, en 1998, en un artículo que aparece sin firma, apunta que en la década de los veinte no se ignoraba si ganaría la batalla de la prosa americana el adornado estilo de Fitzgerald o la musculosa dicción
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Adem s de favorecer la
2019-05-30
Además de favorecer la configuración del capital literario, la crítica encarna un momento esencial, el último, del proceso de producción de la obra literaria (Bourdieu: 258); por su parte, Owen no solo funge de intermediario en esta “historia de las rivalidades” como crítico, sino que forma parte de
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Es un hecho innegable que la
2019-05-30
Es un hecho innegable que la descripción que Servando Teresa de Mier plasma en sus Memorias (escritas en las cárceles inquisitoriales de Nueva España entre 1818 y 1820) sobre su estadía forzada en Europa por más de veinte años presenta exageraciones sobre el castigo que la Inquisición española le im
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br Conflict of interest br Acknowledgments
2019-05-29
Conflict of interest Acknowledgments This research was supported by the Grants from the National Natural Science Foundation of China (No. 31270820 and No. 81230061 to Wei-Dong Han, No. 81402567 to Ya-jing Zhang) and was partially supported by a Grant from the National Basic Science and Develop
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CLL associated HLH was first
2019-05-29
CLL associated HLH was first documented in the form of a case series report which included six patients treated for CLL who subsequently developed the phagocytic syndrome months to years later.[7] As these cases occurred prior to publication of the 1991 HLH diagnostic guidelines, the authors postula
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br Discussion Our results confirm
2019-05-29
Discussion Our results confirm that germline variations in the TPMT gene are associated with treatment outcome in children with ALL [5]. The ability of TPMT to catalyze S-methylation and inactivate 6-mercaptopurine makes it a major determinant of 6-mercaptopurine toxicity. Furthermore, reduced TP
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guanidine hydrochloride EBV occasionally reactivates to swit
2019-05-29
EBV occasionally reactivates to switch its replication mode from latent to lytic, producing a large number of infectious virions with the lysis of host cells [7]. Although reactivation is dangerous for the virus, its triggering factors have not yet been identified. EBV reactivation is associated not
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Ashuntantang and colleagues should have also highlighted oth
2019-05-29
Ashuntantang and colleagues should have also highlighted other prominent factors in the region that contribute to such poor outcomes, including a dearth of workforce ( In a study in , Adam Bennet and colleagues have applied innovative methods to do an analysis of household survey data providing evi
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A year old male with known dextrocardia
2019-05-29
A 52-year-old male with known dextrocardia and CCTGA presented with a 2-month history of recurrent presyncope and effort intolerance. His examination revealed a resting pulse rate of 52beats/min (bpm) and a blood pressure of 130/80mmHg. The apex beat and heart sounds were appreciated on the right si
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